Symbol
Name
ID

Erbb2
erb-b2 receptor tyrosine kinase 2
MGI:95410

Phenotype annotations related to cardiovascular system

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Mouse Phenotypes

cardiovascular system phenotype

abnormal vitelline vasculature morphology

absent vitelline blood vessels

abnormal atrium myocardium morphology

abnormal myocardial fiber morphology

abnormal myocardial trabeculae morphology

absent trabeculae carneae

absent myocardial trabeculae

decreased atrioventricular cushion size

abnormal heart atrium morphology

dilated heart atrium

decreased heart left ventricle septal wall thickness

enlarged heart

cardiac hypertrophy

abnormal heart ventricle morphology

decreased heart left ventricle posterior wall thickness

increased heart ventricle size

thin ventricular wall

dilated cardiomyopathy

abnormal blood circulation

hemorrhage

poor circulation

decreased ventricle muscle contractility

abnormal cardiac muscle relaxation

irregular heartbeat

atrioventricular block

prolonged QT interval

Availability

Mouse Genotype

Erbb2^l11Jus8/Erbb2^l11Jus8

Erbb2^tm1Cbm/Erbb2^tm1Cbm

Erbb2^tm1Gne/Erbb2^tm1Gne

Erbb2^tm1Haus/Erbb2^tm1Haus

Erbb2^tm1Mul/Erbb2^tm1Mul

Erbb2^tm2Mul/Erbb2^tm2Mul

Erbb2^{tm8.1(Erbb2)Mul}/Erbb2^{tm8.1(Erbb2)Mul}

Erbb2^tm1Cbm/Erbb2^tm2.1Cbm

Erbb2^tm1Klee/Erbb2^tm1Klee
Myl2^tm1(cre)Krc/Myl2⁺ (conditional)

Erbb2^tm1Klee/Erbb2^tm1Klee
Tg(Ckmm-cre)1Lrsn/0 (conditional)

Erbb2^tm1Cbm/Erbb2^tm2Cbm
Myl2^tm1(cre)Krc/Myl2⁺ (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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